Cystic fibrosis (CF) is a relatively common genetic disease caused by mutations in a pair of  genes located on chromosome 7. Every cell in the body (except the sex cells) has 46 chromosomes (23 pairs, one half inherited from the mother and the other half from the father). Genes on these chromosomes form the body's blueprint for producing proteins that control body functions. There is a gene on each number 7 chromosome that is responsible for the production of a protein called cystic fibrosis transmembrane regulator (CFTR). Mutations in this gene lead to absent or defective CFTR production, causing CF. Almost 1,000 different CF mutations have been identified, although some are much more common than others.

Since Project CF is a research project, this site is purely a research site. It contains links to expert sites on CF. The information presented here is based on works already done by the experts. Please feel free to contact me.

Joseph Oriko